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Family History and BMI Correlate with Blood Pressure: A Cross-Section Study

Received: 21 August 2018     Accepted: 9 October 2018     Published: 7 November 2018
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Abstract

Hypertension is a general disease which is caused by complex polygenic inheritance, environment and multiple risk factors. The specific proportion of genes and the environment, however, was different in the previous published studies. The objective of this study is to identify the correlation between family history of hypertension (FH) and body mass index(BMI) with blood pressure based on cross section data. The correlation and interaction of FH and BMI on blood pressure is measured of 96646 patients with complete data which is selected from the database of screening in hypertension registry and follow-up management system by statistical analysis. 46.52% of patients with high blood pressure had FH, and 43.52% of patients with high blood pressure are overweight or obese. The average onset age of hypertension in cases without hypertension family history is 65.11 years old, and the average onset age in cases with hypertension family history is 60.17 years old. The average onset age of hypertension in cases in normal weight subjects is 64.01 years old, while the average age in overweight and obese subjects are respectively 61.55 and 61.11 years old. The independent effect of FH and BMI on SBP are OR=1.01 (95%CI:0.98~1.06) and OR=1.26 (95%CI:1.04~1.54) respectively, and the joint effect is OR=1.43 (95%CI:1.11~1.83); the independent effect on DBP are OR=1.75 (95%CI:1.66~1.85) and OR=1.99 (95%CI:1.89~2.09) respectively, and the joint effect is OR=2.37 (95%CI:2.25~2.50). The pure attributable proportion of interaction of FH and BMI on SBP is 37.21%, and that on DBP is 27.01%. FH and BMI have positive interaction with blood pressure. FH and BMI have positive correlation with blood pressure. Both of them (FH and BMI) can simultaneously increase the risk of hypertension, and lead to earlier age of onset.

Published in World Journal of Public Health (Volume 3, Issue 4)
DOI 10.11648/j.wjph.20180304.12
Page(s) 111-117
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Family History, Body Mass Index (BMI), Correlation, Interaction, Blood Pressure

References
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Cite This Article
  • APA Style

    An-le Li, Yue-qin Shao, Hong Yuan, Yi-ying Zhang. (2018). Family History and BMI Correlate with Blood Pressure: A Cross-Section Study. World Journal of Public Health, 3(4), 111-117. https://doi.org/10.11648/j.wjph.20180304.12

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    ACS Style

    An-le Li; Yue-qin Shao; Hong Yuan; Yi-ying Zhang. Family History and BMI Correlate with Blood Pressure: A Cross-Section Study. World J. Public Health 2018, 3(4), 111-117. doi: 10.11648/j.wjph.20180304.12

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    AMA Style

    An-le Li, Yue-qin Shao, Hong Yuan, Yi-ying Zhang. Family History and BMI Correlate with Blood Pressure: A Cross-Section Study. World J Public Health. 2018;3(4):111-117. doi: 10.11648/j.wjph.20180304.12

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  • @article{10.11648/j.wjph.20180304.12,
      author = {An-le Li and Yue-qin Shao and Hong Yuan and Yi-ying Zhang},
      title = {Family History and BMI Correlate with Blood Pressure: A Cross-Section Study},
      journal = {World Journal of Public Health},
      volume = {3},
      number = {4},
      pages = {111-117},
      doi = {10.11648/j.wjph.20180304.12},
      url = {https://doi.org/10.11648/j.wjph.20180304.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjph.20180304.12},
      abstract = {Hypertension is a general disease which is caused by complex polygenic inheritance, environment and multiple risk factors. The specific proportion of genes and the environment, however, was different in the previous published studies. The objective of this study is to identify the correlation between family history of hypertension (FH) and body mass index(BMI) with blood pressure based on cross section data. The correlation and interaction of FH and BMI on blood pressure is measured of 96646 patients with complete data which is selected from the database of screening in hypertension registry and follow-up management system by statistical analysis. 46.52% of patients with high blood pressure had FH, and 43.52% of patients with high blood pressure are overweight or obese. The average onset age of hypertension in cases without hypertension family history is 65.11 years old, and the average onset age in cases with hypertension family history is 60.17 years old. The average onset age of hypertension in cases in normal weight subjects is 64.01 years old, while the average age in overweight and obese subjects are respectively 61.55 and 61.11 years old. The independent effect of FH and BMI on SBP are OR=1.01 (95%CI:0.98~1.06) and OR=1.26 (95%CI:1.04~1.54) respectively, and the joint effect is OR=1.43 (95%CI:1.11~1.83); the independent effect on DBP are OR=1.75 (95%CI:1.66~1.85) and OR=1.99 (95%CI:1.89~2.09) respectively, and the joint effect is OR=2.37 (95%CI:2.25~2.50). The pure attributable proportion of interaction of FH and BMI on SBP is 37.21%, and that on DBP is 27.01%. FH and BMI have positive interaction with blood pressure. FH and BMI have positive correlation with blood pressure. Both of them (FH and BMI) can simultaneously increase the risk of hypertension, and lead to earlier age of onset.},
     year = {2018}
    }
    

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  • TY  - JOUR
    T1  - Family History and BMI Correlate with Blood Pressure: A Cross-Section Study
    AU  - An-le Li
    AU  - Yue-qin Shao
    AU  - Hong Yuan
    AU  - Yi-ying Zhang
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    DO  - 10.11648/j.wjph.20180304.12
    T2  - World Journal of Public Health
    JF  - World Journal of Public Health
    JO  - World Journal of Public Health
    SP  - 111
    EP  - 117
    PB  - Science Publishing Group
    SN  - 2637-6059
    UR  - https://doi.org/10.11648/j.wjph.20180304.12
    AB  - Hypertension is a general disease which is caused by complex polygenic inheritance, environment and multiple risk factors. The specific proportion of genes and the environment, however, was different in the previous published studies. The objective of this study is to identify the correlation between family history of hypertension (FH) and body mass index(BMI) with blood pressure based on cross section data. The correlation and interaction of FH and BMI on blood pressure is measured of 96646 patients with complete data which is selected from the database of screening in hypertension registry and follow-up management system by statistical analysis. 46.52% of patients with high blood pressure had FH, and 43.52% of patients with high blood pressure are overweight or obese. The average onset age of hypertension in cases without hypertension family history is 65.11 years old, and the average onset age in cases with hypertension family history is 60.17 years old. The average onset age of hypertension in cases in normal weight subjects is 64.01 years old, while the average age in overweight and obese subjects are respectively 61.55 and 61.11 years old. The independent effect of FH and BMI on SBP are OR=1.01 (95%CI:0.98~1.06) and OR=1.26 (95%CI:1.04~1.54) respectively, and the joint effect is OR=1.43 (95%CI:1.11~1.83); the independent effect on DBP are OR=1.75 (95%CI:1.66~1.85) and OR=1.99 (95%CI:1.89~2.09) respectively, and the joint effect is OR=2.37 (95%CI:2.25~2.50). The pure attributable proportion of interaction of FH and BMI on SBP is 37.21%, and that on DBP is 27.01%. FH and BMI have positive interaction with blood pressure. FH and BMI have positive correlation with blood pressure. Both of them (FH and BMI) can simultaneously increase the risk of hypertension, and lead to earlier age of onset.
    VL  - 3
    IS  - 4
    ER  - 

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Author Information
  • Jiading District Center for Disease Control and Prevention, Shanghai, China

  • Jiading District Center for Disease Control and Prevention, Shanghai, China

  • Jiading District Center for Disease Control and Prevention, Shanghai, China

  • Jiading District Center for Disease Control and Prevention, Shanghai, China

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