This paper describes a mechanical ventilator prototype with preclinical test performed on 10 bioporcine models, where tests were performed for eight hours for each individuals, giving the respective life support on different scenarios inducing stress and evaluating that each subject physiological parameters remain and return swiftly to the normal values. The results have shown the capabilities to maintain physiological parameters for each subject under test and present also the capability of monitoring the pulmonary parameter, compliance (C), computed from the pressure-volume hysteresis loop measured by the prototype, so that this is the unique proposed prototype to present this capability at this extended subject samples. The ventilator prototype was designed following the Medicine & Healthcare products Regulatory Agency (MHRA) from United Kingdom (UK), that was the first guidelines for manufactured ventilator system in the pandemic of COVID-19 emergency. Finally the components used in the mechanical ventilator comes from different industrial applications, that its performances were tested for years and its supply were no affected by the surge of the acquisition of critical electro-mechanical components used by the commercial ventilator factories under pandemic situation as COVID-19 pandemic.
| Published in | World Journal of Public Health (Volume 9, Issue 4) |
| DOI | 10.11648/j.wjph.20240904.13 |
| Page(s) | 335-342 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Compliance, COVID-19, Mechanical Ventilator, Pressure-volume Hysteresis Loop, Porcine bio-model, Preclinical Data
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APA Style
Conejo, E., Calderón, E., Araya, C., García, R. (2024). Mechanical Ventilator Development During COVID-19 Crisis: Preclinical Data Analysis from Porcine Bio-model. World Journal of Public Health, 9(4), 335-342. https://doi.org/10.11648/j.wjph.20240904.13
ACS Style
Conejo, E.; Calderón, E.; Araya, C.; García, R. Mechanical Ventilator Development During COVID-19 Crisis: Preclinical Data Analysis from Porcine Bio-model. World J. Public Health 2024, 9(4), 335-342. doi: 10.11648/j.wjph.20240904.13
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Download@article{10.11648/j.wjph.20240904.13,
author = {Elian Conejo and Eduardo Calderón and Carlos Araya and Ralph García},
title = {Mechanical Ventilator Development During COVID-19 Crisis: Preclinical Data Analysis from Porcine Bio-model},
journal = {World Journal of Public Health},
volume = {9},
number = {4},
pages = {335-342},
doi = {10.11648/j.wjph.20240904.13},
url = {https://doi.org/10.11648/j.wjph.20240904.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjph.20240904.13},
abstract = {This paper describes a mechanical ventilator prototype with preclinical test performed on 10 bioporcine models, where tests were performed for eight hours for each individuals, giving the respective life support on different scenarios inducing stress and evaluating that each subject physiological parameters remain and return swiftly to the normal values. The results have shown the capabilities to maintain physiological parameters for each subject under test and present also the capability of monitoring the pulmonary parameter, compliance (C), computed from the pressure-volume hysteresis loop measured by the prototype, so that this is the unique proposed prototype to present this capability at this extended subject samples. The ventilator prototype was designed following the Medicine & Healthcare products Regulatory Agency (MHRA) from United Kingdom (UK), that was the first guidelines for manufactured ventilator system in the pandemic of COVID-19 emergency. Finally the components used in the mechanical ventilator comes from different industrial applications, that its performances were tested for years and its supply were no affected by the surge of the acquisition of critical electro-mechanical components used by the commercial ventilator factories under pandemic situation as COVID-19 pandemic.},
year = {2024}
}
TY - JOUR T1 - Mechanical Ventilator Development During COVID-19 Crisis: Preclinical Data Analysis from Porcine Bio-model AU - Elian Conejo AU - Eduardo Calderón AU - Carlos Araya AU - Ralph García Y1 - 2024/10/31 PY - 2024 N1 - https://doi.org/10.11648/j.wjph.20240904.13 DO - 10.11648/j.wjph.20240904.13 T2 - World Journal of Public Health JF - World Journal of Public Health JO - World Journal of Public Health SP - 335 EP - 342 PB - Science Publishing Group SN - 2637-6059 UR - https://doi.org/10.11648/j.wjph.20240904.13 AB - This paper describes a mechanical ventilator prototype with preclinical test performed on 10 bioporcine models, where tests were performed for eight hours for each individuals, giving the respective life support on different scenarios inducing stress and evaluating that each subject physiological parameters remain and return swiftly to the normal values. The results have shown the capabilities to maintain physiological parameters for each subject under test and present also the capability of monitoring the pulmonary parameter, compliance (C), computed from the pressure-volume hysteresis loop measured by the prototype, so that this is the unique proposed prototype to present this capability at this extended subject samples. The ventilator prototype was designed following the Medicine & Healthcare products Regulatory Agency (MHRA) from United Kingdom (UK), that was the first guidelines for manufactured ventilator system in the pandemic of COVID-19 emergency. Finally the components used in the mechanical ventilator comes from different industrial applications, that its performances were tested for years and its supply were no affected by the surge of the acquisition of critical electro-mechanical components used by the commercial ventilator factories under pandemic situation as COVID-19 pandemic. VL - 9 IS - 4 ER -
Atomic, Nuclear and Molecular Research Center (CICANUM), University of Costa Rica, San Pedro Montes de Oca, Costa Rica
School of Mechanical Engineering, University of Costa Rica, San Pedro Montes de Oca, Costa Rica
School of Electrical Engineering, University of Costa Rica, San Pedro Montes de Oca, Costa Rica
Atomic, Nuclear and Molecular Research Center (CICANUM), University of Costa Rica, San Pedro Montes de Oca, Costa Rica
